(a)

(b)

(c)

(d)

(e)

(f)

Figure 1: Prognostic factors significantly associated with mortality in patients with multiple recurrences of well-differentiated thyroid carcinoma. (a). age >45, (b). stage III/IV disease, (c). angioinvasion, (d). distant metastasis, (e). MACIS score >6, (F). time to recurrence <12 months.