The Cancer Stem Cell Concept in Progression of Head and Neck Cancer

Table 1

Putative CSC makers in solid tumors.

CSC markers	Tumor types	% CSC markers	Minimal cell no.	Refs
		in tumor cells	for tumor formation
CD44^+/CD24^−/low	Breast	11–35	200	[18]
CD44^+	Head and neck	0.1–42	5000	[57]
	Prostate	0.3–38	100	[26]
CD44^+/EpCA𝑀^hi	Colon	0.03–38	200	[31]
CD44^+/CD24^−/ESA^+	Pancreas	0.2–0.8	100	[27]
ALDH1^+	Breast	3–10	500	[71]
CD133^+	Brain	6–29	100	[21]
	Brain	2-3	500	[39]
	Colon	1.8–25	200	[40]
	Colon	0.7–6	3000	[27]
	Head and neck	0.8–4.2	1000	[60]
	Pancreas	1–3	500	[32]
	Lung	0.32–22	10^4	[19]
Side population	Prostate	0.05–0.2	100	[33]
ABCG5^+	Melanoma	1.6–20	10^6	[30]