Review Article
Update in Antiepidermal Growth Factor Receptor Therapy in the Management of Metastatic Colorectal Cancer
Table 2
Nonstatistical comparison of the results of the
BOND-2 [
23] and BOND-1 study [
1].
| BOND2
| BOND2
| | BOND1
| BOND1
| Cetuximab, irinotecan, and bevacizumab | Cetuximab and bevacizumab | | Cetuximab and irinotecan | Cetuximab alone |
| No. of Patients | 43 | 40 | 218 | 111 | Prior treatment with oxaliplatin (%) | 87 | 89 | 62 | 64 | Response rates (%) | 37 | 20 | 23 | 11 | Time to progression (months) | 7.3 | 4.9 | 4.1 | 1.5 | Median overall survival (months) | 14.5 | 11.4 | 8.6 | 6.9 |
|
|