Review Article

Update in Antiepidermal Growth Factor Receptor Therapy in the Management of Metastatic Colorectal Cancer

Table 2

Nonstatistical comparison of the results of the BOND-2 [23] and BOND-1 study [1].

BOND2 BOND2 BOND1 BOND1
Cetuximab, irinotecan, and bevacizumabCetuximab and bevacizumabCetuximab and irinotecanCetuximab alone

No. of Patients4340218111
Prior treatment with oxaliplatin (%)87896264
Response rates (%)37202311
Time to progression (months)7.34.94.11.5
Median overall survival (months)14.511.48.66.9