Tumor-Stromal Interactions Influence Radiation Sensitivity in Epithelial- versus Mesenchymal-Like Prostate Cancer Cells
Figure 4
Effect of Anti-E-cadherin antibody on tumor-stroma interactions. A. ARCaPM and ARCaPE, cells were pretreated with Anti-E-cadherin antibody (SHEP8-7), cocultured with HS-27a stromal cells for 24 hours, and radiated with 4 Gy. Cell colony forming capacity was assayed using clonogenic assay. ARCaPM data are normalized to ARCaPM control levels, and ARCaPE data are normalized to ARCaPE control levels.
