Research Article
Germline Mutations and Polymorphisms in the Origins of Cancers in Women
Table 1
Genetic loci implicated in hereditary, familial, and sporadic breast cancer susceptibility.
| High penetrance, | Low penetrance, | Low penetrance, | low frequency | low frequency | High frequency |
| BRCA1 | CHEK2 | FGFR2 | BRCA2 | ATM | LSP1 | PTEN | PALB2 | MAP3K1 |
p53 | BRIP1 | TGFB1 | STK11 | | TOX3 | | | 2q35 | | | 8q |
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