Review Article
Thyroid Cancer: Current Molecular Perspectives
Table 2
Prevalence of major genetic alterations in all of the TCs but MTC.
| Genes | PTC | FTC | ATC |
| BRAF | 45% | RARE | 20% | RAS | 10%–20% | 40%–50% | 50%–60% | NTRK1 | 5% | — | — | PI3K/AKT and PTEN | — | 7% | 15% | TP53 | RARE | RARE | 60%–80% | CTNNB1 | RARE | RARE | 66% | RET/PTC | 25%–30% | — | — | PAX8/PPAR | — | 35% | — |
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