Research Article

Architectural Heterogeneity in Tumors Caused by Differentiation Alters Intratumoral Drug Distribution and Affects Therapeutic Synergy of Antiangiogenic Organoselenium Compound

Figure 4

Change in relative vascular permeability and vascular volume as a result of treatment with MSC in H69 (a), A549 (b), A253 (c), PDSCC (d), and WDSCC (e) tumors as assessed by DCE-MRI.
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(a) H69
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(b) A549
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(c) A253
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(d) Patient SCC (Poorly-diff)
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(e) Patient SCC (Well-diff)