Role of Chemokine Network in the Development and Progression of Ovarian Cancer: A Potential Novel Pharmacological Target

Table 2

CXCR4 and CXCL12 expression in human ovarian carcinomas and tumor ascite cells.

Ovarian carcinoma	CXCR4 expression		CXCL12 expression		References
Solid tumors (positive/total, %)	Protein	mRNA	Protein	mRNA
8/10, 80%	X	X	X	X	[81]
19/20, 95%		X		X	[81]
16/18, 88%	X		X		[25]
26/44, 60%	X				[82]
40/44, 91%			X		[82]
27/30 (metastatic), 91%			X		[82]
23/30 (metastatic), 77%	X				[82]
12/12, 100%	X	X	X	X	[83]
119/128, 93%	X				[87]
128/128, 100%			X		[87]
16/36, 44%	X				[78]
Ascites (positive/total, %)
63/63, 100%			X		[81]
26/26, 100%			X		[78]