Locking Src/Abl Tyrosine Kinase Activities Regulate Cell Differentiation and Invasion of Human Cervical Cancer Cells Expressing E6/E7 Oncoproteins of High-Risk HPV

<table>SKI-606 and Iressa (to a lesser extent) induce morphological changes in HeLa and SiHa cell lines. Untreated (control) cells possess a fibroblast-like (mesenchymal) cell phenotype, whereas 48 hours treatment with SKI-606 (5 <svg height="9.6750002" id="M46" style="vertical-align:-2.29482pt" version="1.1" viewbox="0 0 9.6374998 9.6750002" width="9.6374998" xmlns="http://www.w3.org/2000/svg">
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</svg>M) significantly induces a mesenchymal-epithelial transition of these cells in comparison with Iressa-treated cells.</table>

Journal of Oncology

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Figure 3: Locking Src/Abl Tyrosine Kinase Activities Regulate Cell Differentiation and Invasion of Human Cervical Cancer Cells Expressing E6/E7 Oncoproteins of High-Risk HPV 

Figure 3 | Locking Src/Abl Tyrosine Kinase Activities Regulate Cell Differentiation and Invasion of Human Cervical Cancer Cells Expressing E6/E7 Oncoproteins of High-Risk HPV 