Locking Src/Abl Tyrosine Kinase Activities Regulate Cell Differentiation and Invasion of Human Cervical Cancer Cells Expressing E6/E7 Oncoproteins of High-Risk HPV

Figure 6

Immunofluorescence analysis of E-cadherin, 𝛼-, 𝛽-, and 𝛾-catenin expression in HeLa-untreated (control) and SKI-606 as well as Iressa-treated cells. We note that SKI-606-treatment restores the expression patterns of E-cadherin and 𝛼-, 𝛽-, as well as 𝛾-catenin, on cell surfaces and undercoat membrane, at 5 𝜇M concentration, in HeLa cells when compared with Iressa-treated and untreated cells at the same concentrations.