Role of Angiopoietin-2 in Regulating Growth and Vascularity of Astrocytomas

Table 1

Effect of Ang2 on subcutaneous xenograft models of GBM.

	U87MG:Ctl	U87MG:Ang2	U373:Ctl	U373MG:Ang2
	𝑛 = 8	𝑛 = 15	𝑛 = 15	𝑛 = 15
Final Tumor Size (cm^3)	2.01	5.7 *	3.18	5.96
	(SEM 0.3)	(SEM 0.4)	(SEM 0.3)	(SEM 0.5)
		𝑃=4×10^−4		𝑃=6×10^−5
Proliferation Index	0.23	0.75*	0.042	0.28
		𝑃=.0042		𝑃=.001
MVD (vessels/HPF) mean of 10 counts	2.12	9.5*	3	3.9*
	(SEM 0.1)	(SEM 0.1)	(SEM 0.1)	(SEM 0.2)
		𝑃=.001		𝑃=.001

SEM = Standard Error of Mean
^∗indicates statistical significance.