Effects of HIF-1𝛼 and HIF2𝛼 on Growth and Metabolism of Clear-Cell Renal Cell Carcinoma 786-0 Xenografts

Figure 6

Oxidative stress and DNA damage/repair in CCRCC 786-0 tumors. (a–d) 8-OH-Guanosine staining (oxidative stress marker) (${}^{*}P=.001$). (e–h) $\gamma$H2A.X staining (double-stranded DNA damage) (${}^{*}P=.004$). (i–l) OGG1 expression (${}^{*}P=.006$). ${}_{}{}^{*}P$ values were calculated using an ANOVA test.

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