]>Outcome of Combined Hepatocellular and Cholangiocarcinoma of the Liver : Table 4
Table 4: Cox proportional multivariate analysis of factors associated with cancer-specific mortality.

CharacteristicsGroupHR(95% CI)P Value

Age1.00(0.99–1.01).56

GenderMale1.00
Female1.27(0.93–1.71).14

RaceWhite1.00
Black1.41(0.93–2.13).10
Others1.36(0.91–2.03).13

SEER StageLocalized1.00
Regional1.59(1.10–2.33).018
Distant2.50(1.70–3.61)<.0001

GradeLow1.00
High1.45(0.90–2.32).13
Unknown1.02(0.66–1.57).94

Civil StatusMarried1.00
Widowed1.21(0.81–1.83).36
Divorced
/Separated
0.96(0.59–1.54).85
Single1.01(0.68–1.49).96
Unknown0.61(0.31–1.24).17

Diagnosis Year1973–19881.00
1989–20040.81(0.60–1.09).16

RadiationNo1.00
Yes0.82(0.50–1.38).47

Cancer Directed SurgeryNo1.00
Transplantation0.25(0.13–0.50)<.0001
Resection0.26(0.15–0.44)<.0001
Other Surgery0.28(0.15–0.53)<.0001

HR: hazard ratio; CI: confidence interval; low grade: well differentiated/moderately differentiated; high grade: poorly differentiated/undifferentiated; other surgery: local surgery plus unknown surgery; SEER: surveillance, epidemiology, and end results.