MicroRNAs as Novel Biomarkers for Breast Cancer

Table 1

MiRNAs with altered expression in malignancy.

Tissue/tumor type	Increased expression	Decreased expression
Breast [26, 27]	miR-21, miR-29b-2	miR-125b, miR-145 miR-10b, miR-155, miR-17-5p, miR-27b
Ovarian [28, 29]	miR-141, miR-200(a-c), miR-221	let-7f, miR-140, miR-145, miR199a, miR-424
Endometrial [30–32]	miR-103, miR-107, miR-185, miR-205, miR-210, miR-449	miR-99b, miR-152, miR-193, miR-204, miR-221, let-7i
Glioblastoma [4, 25]	miR-221, miR-21	miR-181a, miR-181b, miR-181c
Chronic lymphocytic leukaemia [24]		miR-15, miR-16
Lymphoma [4, 11]	miR-155, miR-17-92cluster	miR-15a
Colorectal [4, 11, 25]	miR-10a, miR-17-92 cluster, miR-20a, miR-24-1, miR-29b-2, miR-31	miR-143, miR-145, let-7
Thyroid [4, 25]	miR-221, miR-222, miR-146, miR-181b, miR-197, miR-346
Hepatocellular [4, 25]	miR-18, miR-224	miR-199a, miR-195, miR-200a, miR-125a
Testicular [11]	miR-372, miR-373
Pancreatic [4, 11, 25]	miR-221, miR-376a, miR301, miR-21, miR-24-2, miR-100, miR-103-1,2, miR-107, miR-125b-1	miR-375
Cholangiocarcinoma [25]	miR-21, miR-141, miR-200b
Prostate [11]	let-7d, miR-195, miR-203	miR-128a
Gastric [4, 11, 25]	miR-223, miR-21, miR-103-2	miR-218-2
Lung [4, 11, 25]	mir-17-92 cluster, miR-17-5p	let-7 family