Ganglioside GM3 Is Antiangiogenic in Malignant Brain Cancer

Table 1

Association of GM3 levels to the vascularity of experimental brain ${tumors}^{*}$.

	Ganglioside Distribution		Vascularity
Brain Tumors	GM3	Complex Gangliosides
Mouse
EPEN	High	Low	Low
CBT-1	High	Low	Low
CBT-3	High	Low	Low
CBT-4	Low	high	High
CT-2	Low	High	High
CT-2A	Low	High	High
Human
U87MG	Low	High	High

${}^{*}$All mouse brain tumors were produced from implantation of 20-methylcholantherene into the ventricle (EPEN), the cerebrum (CT), or the cerebellum (CBT) of C57BL/6J mice as we previously described [43].