The Gap between Tobacco Treatment Guidelines, Health Service Organization, and Clinical Practice in Comprehensive Cancer Centres

Table 1

According to Hughes J. R. Nicotine withdrawal symptoms. Effects of abstinence from tobacco: valid symptoms and time course.

Withdrawal Symptoms	Peak	Duration
Anger/irritability/frustration	Within first week	2, 4 or more weeks
Anxiety	3 day	2 weeks
Dysphoria (depressed mood and negative affect)	1, 2, 3 weeks	4 weeks
Difficulty concentrating	2, 3 days	3, 4 weeks
Impatience		3, 4, or more weeks
Insomnia (sleep fragmentation)
Restlessness	1, 3 days	2, 4 weeks