Short-Term Exposure to Tobacco Toxins Alters Expression of Multiple Proliferation Gene Markers in Primary Human Bronchial Epithelial Cell Cultures

Figure 2

Although seen with many carcinogen exposures as occasional finding at higher concentrations, striking blebbing of the cytoplasmic membrane was noted with 24-hour N-nitrosodiethylamine exposure at extremely low concentration (1 ng/mL) detected by phase contrast microscopy at 60x. Inset: negative control as comparison with smooth and regular cell surface.