Short-Term Exposure to Tobacco Toxins Alters Expression of
Multiple Proliferation Gene Markers in Primary Human Bronchial
Epithelial Cell Cultures

<table>Electron microscopy shows striking and consistent nuclear and nucleolar changes with markedly increased size and changes in shape including elongation and multiple enlarged and/or irregularly shaped nucleoli and nucleolus appearing to span the inner diameter of the nucleus. The electron dense cytoplasmic granular material is present only in the negative control.  NNK is represented in multiple images to show the pleomorphism in the toxin-induced nuclear changes. Direct magnification: 6500x, Print magnification: 11200x at 7 inch.</table>

Journal of Oncology

fig3

Figure 3

Figure 3: Short-Term Exposure to Tobacco Toxins Alters Expression of
Multiple Proliferation Gene Markers in Primary Human Bronchial
Epithelial Cell Cultures 

Figure 3 | Short-Term Exposure to Tobacco Toxins Alters Expression of
Multiple Proliferation Gene Markers in Primary Human Bronchial
Epithelial Cell Cultures 

Journal of Oncology

Short-Term Exposure to Tobacco Toxins Alters Expression of Multiple Proliferation Gene Markers in Primary Human Bronchial Epithelial Cell Cultures

Figure 3