352616.fig.001
Figure 1: Diagrammatic representation of homophilic E-cadherin interaction and homotypic cell adhesion within the epithelium. E-cadherin cis-dimers form transhomodimers with E-cadherin molecules on neighbouring cells to facilitate epithelial integrity. Note that the exact mechanism of homophilic E-cadherin interaction is unclear. For clarity, only E-cadherin is represented within adherens junctions.