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Figure 2: E-cadherin and the Cytoplasmic Cell adhesion Complex. E-cadherin is stabilised at the cell surface by its link to the actin cytoskeleton via β-catenin, α-catenin, and, possibly, Epithelial Protein Lost in Neoplasm (EPLIN). p120ctn stabilises the CCC by preventing clathrin-mediated endocytosis.