Cancer Stem Cells in Head and Neck Squamous Cell Carcinoma
Figure 3
CSC Theory and Treatment Response. (a) Current chemotherapy and radiation treatment regimens with broad cytotoxic effects kill the bulk of differentiated tumor cells with preferential sparring of resistant CSCs, giving apparent volumetric reduction of tumor but subsequent recurrence. (b) Targeted therapy preferentially kills CSC leaving nonrenewing cells with eventual tumor death.
