Initial In Vivo Quantification of Tc-99m Sestamibi Uptake as a Function of Tissue Type in Healthy Breasts Using Dedicated Breast SPECT-CT

Table 1

Results tabulated from the seven patients show no preferential uptake of MIBI in glandular or fatty breast tissue. Average measured uptake values are noisy due to count limitations of in vivo SPECT measurements.

Subject	Total breast	Adipose tissue			Glandular tissue
		Minimum	Cross-point	95% interval	Minimum	Cross-point	95% interval
	Mean (μCi/mL)	Mean (μCi/mL)	Mean (μCi/mL)	Mean (μCi/mL)	Mean (μCi/mL)	Mean (μCi/mL)	Mean (μCi/mL)
1	0.176 ± 0.486	0.154 ± 0.624	0.155 ± 0.623	0.158 ± 0.624	0.20 ± 0.753	0.196 ± 0.747	0.196 ± 0.745
2	0.061 ± 0.388	0.055 ± 0.458	0.054 ± 0.451	0.053 ± 0.471	0.09 ± 0.579	0.082 ± 0.555	0.084 ± 0.552
3	0.168 ± 0.506	0.175 ± 0.601	0.176 ± 0.601	0.179 ± 0.611	0.120 ± 0.492	0.139 ± 0.547	0.129 ± 0.504
4	0.069 ± 0.299	0.066 ± 0.366	0.065 ± 0.360	0.063 ± 0.347	0.077 ± 0.380	0.078 ± 0.394	0.079 ± 0.394
5	0.117 ± 0.520	—	—	—	—	—	—
6	0.038 ± 0.206	—	—	—	—	—	—
7	0.064 ± 0.385	—	—	—	—	—	—
Total	0.10 ± 0.16	0.11 ± 0.26	0.11 ± 0.26	0.11 ± 0.26	0.12 ± 0.27	0.12 ± 0.27	0.12 ± 0.27