Review Article

Tumor Angiogenesis: Pericytes and Maturation Are Not to Be Ignored

Figure 2

Delta-like ligand 4 (DLL4) and its expression in bone marrow-derived cells. The expression level of DLL4 dictates the role of bone marrow-derived cells in the neovasculature. DLL-4-Notch signaling controls tip cell versus stalk cell fate in endothelial cells and has a regulatory effect on pericyte formation [66].
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