Rapid Stereomicroscopic Imaging of HER2 Overexpression in Ex Vivo Breast Tissue Using Topically Applied Silica-Based Gold Nanoshells

Figure 2

𝑍-stack two-photon luminescence images of HER2-positive and HER2-negative tissue incubated with HER2-targeted nanoshells for 5 minutes at 37°C. Each progressive image represents an increase in depth penetration of 5 μm. Magnification = 20x. Scale bar = 50 μm.