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Journal of Oncology
Volume 2012 (2012), Article ID 370272, 8 pages
http://dx.doi.org/10.1155/2012/370272
Review Article

FDG-PET in Follicular Lymphoma Management

1Nuclear Medicine Department, University Hospital-ICO-Gauducheau, INSERM UMR 892 Team 13, 44093 Nantes, France
2Hematology Department, University Hospital, INSERM UMR 892 Team 10, 44093 Nantes, France
3Radiology Department, University Hospital, INSERM UMR 892 Team 13, 44093 Nantes, France

Received 19 April 2012; Accepted 26 June 2012

Academic Editor: Michiel W. M. van den Brekel

Copyright © 2012 C. Bodet-Milin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

18-Fluoro-deoxyglucose positron emission tomography/computerised tomography (FDG PET/CT) is commonly used in the management of patients with lymphomas and is recommended for both initial staging and response assessment after treatment in patients with diffuse large B-cell lymphoma and Hodgkin lymphoma. Despite the FDG avidity of follicular lymphoma (FL), FDG PET/CT is not yet applied in standard clinical practice for patients with FL. However, FDG PET/CT is more accurate than conventional imaging for initial staging, often prompting significant management change, and allows noninvasive characterization to guide assessment of high-grade transformation. For restaging, FDG PET/CT assists in distinguishing between scar tissue and viable tumors in residual masses and a positive PET after induction treatment would seem to predict a shorter progression-free survival.