Age of 40 Years or Younger Is an Independent Risk Factor for Locoregional Failure in Early Breast Cancer: A Single-Institutional Analysis in Saudi Arabia
Table 2
Results of the Kaplan-Meier analysis.
Factor
2-year locoregional failure-free survival
95% CI
value
Age
0.005
Age ≤40
54
0.86
0.75–0.98
Age >40
158
0.98
0.95–1.00
Menopausal status
0.52
Premenopausal
129
0.99
0.97–1.00
Postmenopausal
84
0.97
0.91–1.00
BMI
0.31
BMI <30
72
0.95
0.88–1.00
BMI ≥30
83
0.97
0.92–1.00
T stage
0.03
Tis, T0–2
159
0.98
0.95–1.00
T3-4
47
0.89
0.78–1.00
N stage
0.13
N0
77
1.00
1.00-1.00
N+
128
0.94
0.88–1.00
Grading
0.27
G1-2
80
1.00
1.00-1.00
G3
93
0.93
0.86–1.00
Tumor subtype
0.03
Luminal A
75
0.91
0.83–0.99
Others*
114
0.99
0.97–1.00
Lymphovascular status
0.02
LV0
67
1.00
1.00-1.00
LV1
68
0.90
0.79–1.00
Type of surgery
0.59
Mastectomy
121
0.96
0.91–1.00
BCS
91
0.97
0.92–1.00
Residual tumor status
0.56
R0
163
0.97
0.93–1.00
R1
15
1.00
1.00-1.00
Abbreviations. BMI: body mass index; *: luminal B, Her2 overexpressing, or triple negative; BCS: breast conserving surgery; CI: confidence interval.