N-Acetyltransferase 1 (NAT1) Genotype: A Risk Factor for Urinary Bladder Cancer in a Lebanese Population

Table 5

Multivariate logistic regression analysis testing for NAT1*14A as a potential effect modifier.The used best-fit model is based on the following variables in the crude model: income, family history, passive smoking at the work place, occupational exposure to combustion fumes, previous history of prostate-related symptoms, and history of urinary tract infections.

Variable	Testing for independent effect	Testing for NAT1*14 as a potential effect modifier
		NAT1* 14A (yes)	NAT1* 14A (no)
	Adjusted OR (CI)	Adjusted OR (CI)	Adjusted OR (CI)
Income (reference < 500 $/month)
500–1000	2.12; (0.41–11.04)	0.58; (0.015–22.29)	4.82; (0.47–49.9)
>1000	6.2; (0.77–50.04	1.39; (0.013–145.7)	7.26; (0.38–137.9)
Smoking	1.02*; (1.00–1.037)	1.02; (0.98–1.06)	1.02*; (1.00–1.043)
Occupational exposure to combustion fumes (reference none)	3.72; (0.74–18.8)	2.03; (0.054–75.45)	4.47; (0.47–42.25)
Prostate-related symptoms (reference: none)	6.42*; (0.92–39.1)	2.35; (0.00−)	1.04; (0.039–28.12)
Allele (reference: none)
NAT1*14A	7.86*; (1.53–40.39)
NagelKerke 𝑅^2	0.57	0.62	0.47

*Significant at or less than 0.05.