DNA Damage Response is Prominent in Ovarian High-Grade Serous Carcinomas, Especially Those with Rsf-1 (HBXAP) Overexpression

<table>Box plot for the correlation of pChk2 immunostaining intensity and percentage of tumor cells showing pChk2 staining among 206 ovarian tumor tissues. The percentage of pChk2 positive cells correlates with intensity grade: percent pChk2 positive cells in 3+ cases &gt; 2+ cases &gt; 1+ cases (<svg height="11.0625" id="M4" style="vertical-align:-0.30096pt" version="1.1" viewbox="0 0 71.775002 11.0625" width="71.775002" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,11.0625)">
<g transform="translate(72,-63.15)">
<text transform="matrix(1,0,0,-1,-71.95,63.5)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑃</tspan>
<tspan style="font-size: 12.50px; " x="10.890113" y="0">&lt;</tspan>
<tspan style="font-size: 12.50px; " x="22.930502" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="29.182001" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="32.307751" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="38.559254" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="44.810753" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="51.062252" y="0">1</tspan>
</text>
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</svg>, nonparametric one-way ANOVA test).</table>

Journal of Oncology

fig2

Figure 2

Figure 2: DNA Damage Response is Prominent in Ovarian High-Grade Serous Carcinomas, Especially Those with Rsf-1 (HBXAP) Overexpression 