Journal of Oncology / 2012 / Article / Tab 2 / Clinical Study
Retrospective Study of Selective Submandibular Neck Dissection versus Radical Neck Dissection for N0 or N1 Necks in Level I Patients with Oral Squamous Cell Carcinoma Table 2 Characteristics of patients who underwent neck dissection (clinically N0 neck/clinically N1 neck).
Type of neck dissectionClinically N0 neck (110) Clinically N1 neck (68) SMND (77) MRND (33) P valueSMND (32) RND (36) P valuePrimary tumor site
0.825 Tongue 28 (36.4%) 13 (39.4%)
0.923 14 (43.8%) 13 (36.1%) Lower gum 31 (40.3%) 13 (39.4%) 11 (34.4%) 14 (38.9%) Upper gum 7 (9.1%) 3 (9.1%) 3 (9.4%) 4 (11.1%) Buccal mucosa 6 (7.8%) 3 (9.1%) 1 (3.1%) 3 (8.3%) Oral floor 2 (2.6%) 1 (3.0%) 3 (9.4%) 2 (5.6%) Others 3 (3.9%) 0 (0.0%) 0 (0.0%) 0 (0.0%) Clinical tumor stage cT1/255 (71.4%) 23 (69.7%)
0.513 10 (31.3%) 9 (25.0%) 0.381 cT3/422 (28.6%) 10 (30.3%) 22 (68.7%) 27 (75.0%) Tumor differentiation Poorly differentiated 5 (6.5%) 2 (6.1%)
0.982 2 (6.3%) 2 (5.6%) 0.991 Moderately differentiated 22 (28.6%) 10 (30.3%) 9 (28.1%) 10 (27.8%) Well differentiated 50 (64.9%) 21 (63.6%) 21 (65.6%) 24 (66.7%) Mode of invasion Grade 1–3 58 (75.3%) 23 (69.7%)
0.348 22 (68.8%) 23 (63.9%) 0.435 Grade 4 19 (24.7%) 10 (30.3%) 10 (31.2%) 13 (36.1%) Neoadjuvant chemoradiotherapy 26 (33.8%) 12 (36.4%) 0.479 19 (59.4%) 19 (52.8%) 0.325 Pathological nodal stage
0.603 pN0 72 (93.5%) 29 (87.9%) 5 (15.6%) 6 (16.7%) 0.828 pN1 4 (5.2%) 3 (9.1%) 24 (75.0%) 25 (69.4%) pN2b 1 (1.3%) 1 (3.0%) 3 (9.4%) 5 (13.9%) Extracapsular spread 1 (1.3%) 2 (6.1%) 0.214 3 (9.4%) 4 (11.1%) 0.567 Adjuvant chemoradiotherapy 5 (6.5%) 4 (12.1%) 0.264 2 (6.3%) 4 (11.1%) 0.395
SMND: selective submandibular neck dissection; RND: radical neck dissection; MRND: modified radical neck dissection.