Clinical Study

Retrospective Study of Selective Submandibular Neck Dissection versus Radical Neck Dissection for N0 or N1 Necks in Level I Patients with Oral Squamous Cell Carcinoma

Table 2

Characteristics of patients who underwent neck dissection (clinically N0 neck/clinically N1 neck).

 Type of neck dissectionClinically N0 neck (110)Clinically N1 neck (68)
SMND (77)MRND (33) P valueSMND (32)RND (36)P value

Primary tumor site 0.825
 Tongue28 (36.4%)13 (39.4%) 0.92314 (43.8%)13 (36.1%)
 Lower gum31 (40.3%)13 (39.4%)11 (34.4%)14 (38.9%)
 Upper gum7 (9.1%)3 (9.1%)3 (9.4%) 4 (11.1%)
 Buccal mucosa6 (7.8%)3 (9.1%)1 (3.1%)3 (8.3%)
 Oral floor2 (2.6%)1 (3.0%)3 (9.4%)2 (5.6%)
 Others3 (3.9%)0 (0.0%)0 (0.0%)0 (0.0%)
Clinical tumor stage
  cT1/255 (71.4%)23 (69.7%) 0.51310 (31.3%) 9 (25.0%)0.381
  cT3/422 (28.6%)10 (30.3%)22 (68.7%)27 (75.0%)
Tumor differentiation
 Poorly differentiated5 (6.5%)2 (6.1%) 0.9822 (6.3%)2 (5.6%)0.991
 Moderately differentiated22 (28.6%)10 (30.3%) 9 (28.1%)10 (27.8%)
 Well differentiated50 (64.9%)21 (63.6%)21 (65.6%)24 (66.7%)
Mode of invasion
 Grade 1–358 (75.3%)23 (69.7%) 0.34822 (68.8%)23 (63.9%)0.435
 Grade 419 (24.7%)10 (30.3%)10 (31.2%)13 (36.1%)
Neoadjuvant chemoradiotherapy26 (33.8%)12 (36.4%)0.47919 (59.4%)19 (52.8%)0.325
Pathological nodal stage 0.603
 pN072 (93.5%)29 (87.9%) 5 (15.6%) 6 (16.7%)0.828
 pN14 (5.2%)3 (9.1%)24 (75.0%)25 (69.4%)
 pN2b1 (1.3%)1 (3.0%)3 (9.4%)5 (13.9%)
Extracapsular spread1 (1.3%)2 (6.1%)0.2143 (9.4%)4 (11.1%)0.567
Adjuvant chemoradiotherapy5 (6.5%)4 (12.1%)0.2642 (6.3%)4 (11.1%)0.395

SMND: selective submandibular neck dissection; RND: radical neck dissection; MRND: modified radical neck dissection.