Review Article
Potential Role of Garcinol as an Anticancer Agent
Table 1
List of studies investigating the role of Garcinol in different cancer types.
| Type of cancer | Study type | Experimental details | Reference |
| Breast cancer | In vitro | MDA, MB231, MCF-7 | [16] | In vitro | MCF-7, MDA-MB231 | [17] | In vitro | Primary culture, MCF-7 MDA-MB231, AU 565 BT-483 | [18] |
| Burkitt lymphoma | In vitro | TPA induced Ebvirus-EA activated raji cells | [19] |
| Colon cancer | In vitro | HT-29, HCT-116 | [16] | In vitro | HT-29, HCT-116, ICE-6 | [20] | In vitro | HT-29 | [21] | In vivo | Azoxymethane induced colonic aberrant crypt foci F344 rats | [15] |
| Esophageal cancer | In vitro | SEG-1 | [16] |
| Hepatocellular carcinoma | In vitro | MH1C1-HEP G2 | [22] | In vivo | Hep3B | [23] | In vitro | Carcinogen induced liver cancer F344 rats | [24] |
| HeLa cells | In vitro | HeLa core Histones-P300 HAT inhibition | [25] | In vitro | HeLa Histones | [26] |
| Kidney cancer | In vitro | A293 (Human embryonic kinder carcinoma) | [16] |
| Leukemia | In vitro | KBM-5 (chronic Leukemia) | [16] | In vitro | U937, K562, NB4, HL60 | [27] | In vitro | HL-60 | [28] | In vitro | HL-60 | [15] |
| Lung cancer | In vitro | A-549 | [29] |
| Medulloblastoma | In vitro | Daoy, growth factor, | [24] |
| Multiple myeloma | In vitro | U-266 | [16] |
| Pancreatic cancer | In vitro | BxPC3 | [30] | In vitro | Panc-1, BxPC-3 | [31] |
| Prostate cancer | In vitro | LNCaP, C4-2B, PC-3 | [30] | In vitro | PC-3 | [16] |
| Tongue cancer | In vivo | 4-nitroquinoline 1-oxide induced oral carcinogenesis in F344 rats | [32] |
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