Table 1: Dysregulated miRNAs in glioblastoma.

Authors Year Reference Methods Number of miRNA Comparison Upregulation Downregulation Guan et al. miR-15b miR-105 miR-21 miR-128-2 miR-135(b) miR-184 miR-196a miR-302b 2010 [19] TaqMan array 365 GBM versus AA miR-196b miR-302d miR-363 miR-367 miR-383 miR-504 miR-517c miR-601 Ciafrè et al. 2005 [13] Microarray 245 GBM versus NB miR-9 miR-128-1 miR-10b miR-181a miR-21 miR-181b miR-25 miR-181c miR-123 miR-125b-1 miR-125b-2 miR-130a miR-221 Chan et al. 2005 [12] Microarray 180 GBM versus NB miR-21 miR-188 miR-135(b) miR-198 miR-138 miR-202 miR-291-5′ miR-347 Godlewski et al. 2008 [15] Microarray 161 GBM versus ANB miR-10b miR-124a miR-21 miR-128-1 miR-26 miR-128-2 miR-383 miR-137 miR-451 miR-139 miR-486 miR-190 miR-516-35p miR-218 miR-519d miR-299 miR-323 miR-483 miR-511-1 Sasayama et al. 2009 [16] Microarray 127 or 188 GBM versus ANB miR-10b miR-134 miR-21 miR-302c miR-92b miR-329 miR-106b miR-369-3p miR-183 miR-379 Malzkorn et al. 2010 [20] TaqMan 157 GBM versus DA miR-9 miR-184 miR-15a miR-328 miR-16 miR-17 miR-19a miR-20a miR-21 miR-25 miR-28 miR-130b miR-140 miR-210 Rao et al. 2010 [22] LNA array 756 GBM versus AA miR-16 miR-128-1 miR-21 miR-128-2 miR-22 miR-219-2-3p miR-24 miR-34a miR-126 miR-142-5p miR-143 miR-146b-5p miR-155 miR-193a-3p miR-199a/b-3p miR-335 miR-376c miR-381 miR-451 miR-509-3-5p miR-513a-5p miR-552 miR-886-3p/5p

GBM: glioblastoma, AA: anaplastic astrocytoma, NB: normal brain, ANB: adjacent normal brain, and DA: diffuse astrocytoma. Bold: common dysregulated miRNA (more than 3 reports).