Table 1: Dysregulated miRNAs in glioblastoma.

AuthorsYearReferenceMethodsNumber of miRNAComparisonUpregulationDownregulation

Guan et al.miR-15bmiR-105
miR-21 miR-128-2
miR-135(b)miR-184
miR-196amiR-302b
2010 [19]TaqMan array365GBM versus AAmiR-196bmiR-302d
miR-363miR-367
miR-383
miR-504
miR-517c
miR-601

Ciafrè et al.2005 [13]Microarray245GBM versus NBmiR-9miR-128-1
miR-10bmiR-181a
miR-21miR-181b
miR-25miR-181c
miR-123
miR-125b-1
miR-125b-2
miR-130a
miR-221

Chan et al.2005 [12]Microarray180GBM versus NBmiR-21miR-188
miR-135(b)miR-198
miR-138miR-202
miR-291-5
miR-347

Godlewski et al.2008 [15]Microarray161GBM versus ANBmiR-10bmiR-124a
miR-21miR-128-1
miR-26miR-128-2
miR-383miR-137
miR-451miR-139
miR-486miR-190
miR-516-35pmiR-218
miR-519dmiR-299
miR-323
miR-483
miR-511-1

Sasayama et al.2009 [16]Microarray127 or 188GBM versus ANBmiR-10b miR-134
miR-21 miR-302c
miR-92bmiR-329
miR-106bmiR-369-3p
miR-183miR-379

Malzkorn et al.2010 [20]TaqMan157GBM versus DAmiR-9miR-184
miR-15amiR-328
miR-16
miR-17
miR-19a
miR-20a
miR-21
miR-25
miR-28
miR-130b
miR-140
miR-210

Rao et al.2010 [22]LNA array756GBM versus AAmiR-16miR-128-1
miR-21miR-128-2
miR-22miR-219-2-3p
miR-24
miR-34a
miR-126
miR-142-5p
miR-143
miR-146b-5p
miR-155
miR-193a-3p
miR-199a/b-3p
miR-335
miR-376c
miR-381
miR-451
miR-509-3-5p
miR-513a-5p
miR-552
miR-886-3p/5p

GBM: glioblastoma, AA: anaplastic astrocytoma, NB: normal brain, ANB: adjacent normal brain, and DA: diffuse astrocytoma. Bold: common dysregulated miRNA (more than 3 reports).