Modulation of Telomeres in Alternative Lengthening of Telomeres Type I Like Human Cells by the Expression of Werner Protein and Telomerase

Table 2

Effects of WRN and telomerase expression in AGO11395 cells.

	Empty vector	WRN expressing	Telomerase expressing
	AGO11395	AGO11395	AGO11395
STL/cell	9.2–11.4	4.4–7.1	2.8
SV40 origin sequence loss	—	20–25%	40–50%
Telomere length in AFUs	449−577	771–919	872
APBs	not present	present	not present
T-SCE	10.4%	11.9%	9.4%