Human Papillomavirus Genotyping and E6/E7 mRNA Expression in Greek Women with Intraepithelial Neoplasia and Squamous Cell Carcinoma of the Vagina and Vulva

Table 2

Concordance between HPV DNA test (PapilloCheck DNA Microarray) and HPV E6/E7 mRNA test (NucliSENS EasyQ HPV assay) by histological status of samples.

	No. of specimens	Number of specimens positive with		Concordance*	%	Kappa value	𝑃
		HPV DNA test	E6/E7 mRNA test
VAIN I	8	2	0	6/8	75.0	0.00	1.00
VAIN II/III	10	4	6	8/10	80.0	0.62	0.08
Vaginal SCCs	4	2	4	2/4	50.0	0.00	1.00
VIN I	14	5	4	13/14	92.9	0.84	0.005
VIN II/III	14	10	8	8/14	57.1	0.09	1.00
Vulvar SCCs	6	3	5	4/6	66.7	0.33	1.00

*The data represent the number of samples for which the results from PapilloCheck DNA Microarray and NucliSENS EasyQ HPV assay were concordant/total number of samples tested.