Chronic Myelogenous Leukemia Cells Contribute to the Stromal Myofibroblasts in Leukemic NOD/SCID Mouse In Vivo
Figure 1
Characters of the transplanted CML-derived non-adherent mononuclear cells. (a) Smear slides of bone marrow cells obtained from CML patient (AP). Cells were stained with May-Giemsa solution (×400, and ×1000). (b) CD13 and CD33 expressions of the prepared non-adherent mononuclear cells from a CML (AP) patient. (c) FISH analysis. Normal cells appear split red (ABL) and green (BCR) signals, while cells having the translocation give yellow because of the fusion of the 5′ and 3′ signals. 95 cells out of 100 analyzed are positive.
