Vascular Disrupting Agent Arsenic Trioxide Enhances Thermoradiotherapy of Solid Tumors
Figure 3
Representative window chamber imaging of 8 mg/kg i.p. arsenic trioxide-induced vascular damage in FSaII fibrosarcoma grown in nude mice. FSaII tumor was implanted and 7 days later the tumor was imaged before and 2 h after an i.p. injection of 8 mg/kg ATO. The tumor is outlined in black and the boxes have been placed in the areas where typical marked evidence of vascular damage occurred.