Analysis of the mRNA Expression of Chemotherapy-Related Genes in Colorectal Carcinoma Using the Danenberg Tumor Profile Method

Table 1

mRNA expression profiles of 10 genes in the upper and lower thirds of colorectal tumors.

	mRNA (relative gene expression)		𝑃
	Upper third of the tumor	Lower third of the tumor
TS	3.23 ± 1.73	2.94 ± 2.03	N.S.
DPD	0.32 + 0.28	0.40 ± 0.32	0.044
TP	4.04 ± 3.34	5.46 ± 3.86	0.023
FPGS	0.53 ± 0.21	0.48 ± 0.17	N.S.
GGH	23.14 ± 12.72	22.72 ± 15.42	N.S.
DHFR	5.21 ± 2.48	4.43 ± 2.21	N.S.
ERCC1	1.40 ± 0.56	1.34 ± 0.57	N.S.
TOPO-1	2.66 ± 0.94	2.39 ± 0.90	N.S.
VEGF	6.70 ± 4.13	9.32 ± 6.19	0.013
EGFR	1.19 ± 0.57	1.40 ± 0.69	N.S.