Early Pseudoprogression following Chemoradiotherapy in Glioblastoma Patients: The Value of RANO Evaluation

Figure 2

T1-contrast-enhanced magnetic resonance imaging (MRI) documenting pseudoprogression according to Macdonald criteria showing a significant increase in cingulate gyrus enhancing lesion at 1 month after RT/TMZ with subsequent stabilization (stable corticosteroid dose and functional status). FLAIR sequence shows increased signal extending to contralateral hemisphere anticipating true progressive disease.