Development of a Score Predicting Survival after Palliative Reirradiation

Table 1

Patient characteristics.

Characteristic	No.	%
Entire cohort	87
Gender
Male	65	75
Female	22	25
Family status^1
Single	20	23
Married	55	63
Partner	5	6
Missing information	7	8
Karnofsky performance status
90–100	31	36
70–80	30	34
≤60	26	30
Primary tumor site
Prostate	25	29
Breast	9	10
Lung (non-small cell)	10	11
Colorectal	8	9
Bladder	5	6
Kidney	6	7
Skin (malignant melanoma)	3	3
Other	21	24
Dose/fractionation (intention-to-treat)
10 fractions of 3 Gy	24	28
Single fraction of 8 Gy	19	22
5 fractions of 4 Gy	15	17
12–15 fractions of 2.5 Gy	4	5
Other	25	29
Reirradiation target types
Bone metastases	69	79
Brain metastases	5	6
Lung metastases or primary tumor	6	7
Other	7	8
Known brain metastases
No	80	92
One or more	7	8
Known liver metastases
No	68	78
One or more	19	22
Known lung metastases
No	65	75
One or more	22	25
Known adrenal gland metastases
No	76	87
One or more	11	13
Known bone metastases
No	14	16
One or more	73	84
Metastatic spinal cord compression
No	80	92
Yes (radiologic or symptomatic)	7	8
Pleural effusion
No	81	93
Yes (radiologic or symptomatic)	6	7
Number of metastatic sites
0	10	11
1 (e.g., lungs only)	37	43
2 (e.g., lungs and brain)	27	31
3	11	13
4	2	2
Progressive disease outside RT target volume^1
No	27	31
Yes	55	63
Missing information	5	6
Systemic cancer treatment^1
No	23	26
Within 4 weeks before RT	21	24
Within 3 months before RT	14	16
Earlier	17	20
Missing information	12	14
Use of opioid analgetics at start of RT^1
No	21	24
Yes	54	62
Missing information	12	14
Use of steroids at start of RT^1
No	32	37
Yes	38	44
Missing information	17	20
Serum hemoglobin^1
Low^2	66	76
Normal	16	18
Missing information	5	6
Serum albumin^1
Low^2	17	20
Normal	42	48
Missing information	28	32
Serum lactate dehydrogenase^1
Normal^2	14	16
Elevated	35	40
Missing information	38	44
Serum alkaline phosphatase^1
Normal^2	25	29
Elevated	29	33
Missing information	33	38
Serum creatinine^1
Low^2	13	15
Normal	48	55
Elevated	15	17
Missing information	11	13
Serum C-reactive protein^1
Normal^2	20	23
Elevated but less than 30 mg/L	27	31
Elevated 30–60 mg/L	14	16
Elevated >60 mg/L	17	20
Missing information	9	10
Thrombocyte count^1
Low^2	11	13
Normal	45	52
High	19	22
Missing information	12	14
Charlson comorbidity index^1
0	7	8
1-2	44	51
3 or more	28	32
Missing information	8	9
Smoking status^1
Current smoker	34	39
No	34	39
Missing information	19	22

RT: radiotherapy.
¹Missing information in some cases.
²Hematology and blood chemistry results refer to institutional limits of normal; only test results obtained within one week before RT were considered.