Research Article

Androgen Deprivation Therapy and Cardiovascular Risk in Chinese Patients with Nonmetastatic Carcinoma of Prostate

Table 1

Baseline characteristics of patients with and without androgen deprivation therapy.

All ( )ADT ( )No ADT ( ) -value

Age, years <0.01*
Hypertension, (%)276 (37.0)189 (36.6)87 (38.2)0.68
Hypercholesterolemia, (%)79 (10.6)42 (8.1)37 (16.2)<0.01*
Cigarette smoker, (%)284 (38.1)214 (41.4)70 (30.7)<0.01*
Lung disease, (%)26 (3.5)21 (4.1)5 (2.2)0.28
Carcinoma of prostate
 PSA at diagnosis (ng/mL) <0.01*
 Gleason score<0.01*
  2–5, (%)40 (5.4)25 (4.8)15 (6.6)
  6–8, (%)481 (64.6)291 (56.3)190 (83.3)
  9-10, (%)141 (18.9)131 (25.3)10 (4.4)
  Not specified, (%)83 (11.1)70 (13.4)13 (5.7)
Treatment
 Local treatment, (%)486 (65.2)291 (56.3)195 (85.5)<0.01*
 Surgical ADT only, (%)128 (17.2)128 (24.7)
 Medical ADT only, (%)252 (33.8)252 (48.7)
 Medical and Surgical ADT, (%)137 (18.4)137 (26.6)

(comparison between patients with and without ADT).
ADT: androgen deprivation therapy; PSA: prostate specific antigen.