AR-A 014418 Used against GSK3beta Downregulates Expression of hnRNPA1 and SF2/ASF Splicing Factors

<table>Cell viability assay and qRTPCR assay for splicing factors: (a) cell viability assay for dose dependent response of U87 and U373 treated with AR-A 014418 for 48 hrs; (b) qRT-PCR of splicing factors (SRSF1, SRSF5, PTBP1, and hnRNPH3) in U87 glioma cell line after treating cells with Wortmannin and AR-A 014418 in different experiments for 24 hrs. Means <svg height="9.5625" id="M1" style="vertical-align:-0.3003pt" version="1.1" viewbox="0 0 10.1 9.5625" width="10.1" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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Journal of Oncology

fig1

Figure 1

Figure 1: AR-A 014418 Used against GSK3beta Downregulates Expression of hnRNPA1 and SF2/ASF Splicing Factors 