AR-A 014418 Used against GSK3beta Downregulates Expression of hnRNPA1 and SF2/ASF Splicing Factors
Figure 2
Splicing factor regulation. (a) U87 glioma cell lines were treated with TDZ8 (20 μM), Manzamine A (2 μM), and LY294002 (10 μM) for 24 hrs, followed by cytoplasmic and nuclear extraction, studied hnRNPA1 downregulation. Results were evaluated from multiple different experiments. (b) U373 glioma cells were transfected with Akt RNAi and GSK3beta RNAi compared with CNT RNAi, studied SF2/ASF1 and hnRNPA1 downregulation.
