Clinical Study

Hematopoietic Stem-Cell Transplantation in the Developing World: Experience from a Center in Western India

Table 3

Graft versus host disease prophylaxis.

DayProphylaxis regimen

−1Cyclosporine 2.5 mg/kg/dose twice daily

0Peripheral stem-cell transplant

0Cyclosporine 1.5 mg/kg/dose twice daily; continued till day +90 and then gradually taper the dose

+1, +3, +6, +11Methotrexate 15 mg/m2 on D +1, 10 mg/m2 on rest of days [6]

+2, +4, +7, +12Two doses of leucovorin 15 mg/kg/every six hours starting 24 hours after methotrexate