Research Article

The Prevalence of Cardiac Risk Factors in Men with Localized Prostate Cancer Undergoing Androgen Deprivation Therapy in British Columbia, Canada

Table 1

Baseline characteristics of 100 men referred for androgen deprivation therapy.

Age at diagnosis73 (50–87)
Vascular disease25 (25%)
 Coronary artery disease17 (17%)
  Percutaneous coronary intervention9 (9%)
  Coronary artery bypass surgery5 (5%)
 Stroke7 (7%)
 Peripheral arterial disease5 (5%)
Atrial fibrillation5 (5%)
Supraventricular tachycardia1 (1%)
Arrhythmia, not specified4 (4%)
Cardiac pacemaker1 (1%)
Pericarditis1 (1%)
Coronary vasospasm1 (1%)
History of heart failure1 (1%)
Framingham risk category
 High risk49 (65%)*
 Intermediate risk25 (33%)*
 Low risk1 (1%)*
Gleason score
 Moderately differentiated (5–7)30 (30%)
 Poorly differentiated (8–10)70 (70%)
Clinical stage
 T127 (27%)
 T243 (43%)
 T323 (23%)
 T43 (3%)
 X4 (4%)
Initial PSA (ng/mL)
 <59 (9%)
 5–1029 (29%)
 >1062 (62%)
Updated Charlson Comorbidity Index
 082 (82%)
 114 (14%)
 ≥24 (4%)
Hormonal treatment used
 Goserelin72 (72%)
 Leuprolide25 (25%)
 Degarelix2 (2%)
 Bicalutamide 92 (92%)
 Buserelin1 (1%)
 Flutamide 1 (1%)

Expressed as median (range) or number (percentage).
*Expressed as percentage of patients without baseline history of vascular disease.