Research Article

Variability of Oxaliplatin-Induced Neuropathic Pain Symptoms in Each Cycle and Its Implications on the Management of Colorectal Cancer Patients: A Retrospective Study in South Western Sydney Local Health District Hospitals, Sydney, Australia

Table 3

Factors related to the incidence of peripheral neuropathy.

FactorPeripheral neuropathy, N (%)
YesNoNot documented

Sex
 Male141 (43.8)40 (12.4)3 (0.9)
 Female109 (33.8)27 (8.4)2 (0.6)
Treatment regimen
 FOLFOX157 (48.8)49 (15.2)5 (1.5)
 XELOX89 (27.6)16 (4.9)0 (0)
FOLFOX + avastin1 (0.3)0 (0)0 (0)
Oxaliplatin alone3 (0.9)2 (0.6)0 (0)
Age in range (years)
 30–5037 (14.5)8 (2.5)0 (0)
 51–6044 (13.7)7 (2.2)0 (0)
 61–78146 (45.3)38 (11.8)4 (1.2)
 79–8823 (7.1)14 (4.3)1 (0.3)
Previous chemotherapy
 No235 (72.9)62 (19.3)5 (1.5)
 Yes15 (4.7)5 (15.6)0 (0)
Cancer
 Adjuvant181 (56)48 (14.9)4 (1.2)
 Metastatic69 (21.4)19 (5.9)1 (0.3)