A Model of Insulin Resistance in Mice, Born to Diabetic Pregnancy, Is Associated with Alterations of Transcription-Related Genes in Pancreas and Epididymal Adipose Tissue
Figure 3
Relative epididymal adipose tissue weight (a) and adiponectin and leptin (b), and TNF-α and IL-6 (c) mRNA expression in epididymal adipose tissue. Relative liver weight (d) and FAT/CD36 and SREPB-1c mRNA expression in liver (e) of IR and control offspring. The liver and epididymal adipose tissue weights are expressed as milligrams (mg) of the tissue per grams (g) of body weight of mice. The expression of mRNA was quantitatively analyzed by employing real-time RT-PCR as described in Section 2. Values are means SEM, per group of animals. AU: arbitrary units. The quantity of epididymal adipose tissue was positively correlated with the mRNA expression of adiponectin and leptin two obesity-related parameters; = coefficient of correlation between the mass of epididymal adipose tissue and the level of the expression of adipokines (adiponectin and leptin) in each group of animals.
