Review Article

Genetics of Childhood Obesity

Table 1

Childhood obesity loci that have been identified to date and the route through which they were implicated.

CategoryLociCitations

Adult BMI GWAS loci also associated with childhood BMI/obesity in independent studiesFTO, TMEM18, GNPDA2, INSIG2, MC4R, NEGR1, 1q25, BDNF, KCTD15[99]
Adult 2 type diabetes GWAS loci also associated with childhood BMI/obesityHHEX-IDE[100]
GWAS of extreme childhood obesity—novel lociSDCCAG8, TNKS-MSRA[101]
CNV analyses of childhood obesity—novel lociSH2B1, EDIL3, S1PR5, FOXP2, TBCA, ABCB5, ZPLD1, KIF2B, ARL15, EPHA6-UNQ6114, OR4P4-OR4S2-OR4C6[102105]