Treatment of Comorbid Obesity and Major Depressive Disorder: A Prospective Pilot Study for their Combined Treatment

Table 1

Mean (± SD) changes in cardiometabolic risk factors (𝑁=9).

	Baseline	Week 16	Change	P-value
Waist (cm)	104.2±10.5	93.6±12.7	10.6±6.4	.001
Systolic BP	118.4±14.4	110.4±12.4	8.1±8.8	.025
Diastolic BP	72.0±8.2	63.3±8.7	8.7±5.3	.001
Cholesterol
Total (mg/dL)	213.2±27.4	182.7±22.2	30.6±29.3	.014
HDL (mg/dL)	68.9±13.8	61.0±12.7	7.9±10.5	.055
LDL (mg/dL)	127.0±24.8	105.4±19.7	21.6±21.3	.001
Triglycerides (mg/dL)	86.7±34.2	81.1±35.8	5.6±27.6	.562
Glucose (mg/dL)	87.9±5.0	82.8±5.0	5.1±6.4	.042
Insulin (uIU/mL)	7.1±5.2	5.1±4.6	2.0±3.4	.118
Hs-CRP (mg/L)	5.3±5.2	4.9±3.5	0.4±3.7	.748

BP: blood pressure; HDL: high density lipoprotein; LDL: low-density lipoprotein; Hs-CRP: high sensitivity C-reactive protein. P values based on repeated-measures t -tests.