Weight Gain, Obesity, and Psychotropic Prescribing

Table 1

Weight gain treatment options.

Mode or medication	Weight loss produced	Duration of treatment
Behaviour modification	0.5–0.7 kg per week	—
Cognitive-behavioral therapy	4.5 drop in BMI	—
Naltreoxone and buropion	4%	—
Phentermine and topiramate	9%	1 year
Sibutramine	10–15%	<1 year
Orlistat	10.2%, 8.8%	1 year
Orlistat	>10%	2 years
Orlistat	34.6%	?
Amantadine	3.5 kg	3–6 months
Nizatidine	Gained 3 kg less than patients who did not take Nizatidine	16 weeks
Naltexone	5 kg	8 weeks
Topiramate augmentation	10–15 lbs	—
Metformin	15/19 patients lost weight	12 weeks