Research Article
Switching to Aripiprazole as a Strategy for Weight Reduction: A Meta-Analysis in Patients Suffering from Schizophrenia
Table 1
Description of analyzed studies.
| Reference in text =in text | Industry- supported study | Sample size | Age | Diagnosis | BAT | Baseline weight (kilograms) | Aripiprazole treatment duration | Weight change (P value) | Schizophrenia | Schizoaffective | T | SGA |
| Pigott 2003 [11] | + | 155 | 42.2 | 155 (100%) | 0 | 116 | 39 | 75 | 26 | () | Casey 2003 [12] | + | 311 | | 210 (65.3%) | 101 | 24 | 287 | 90.2 | 8 | () | Spurling 2007 [15] | | 24 | | 9 (37.5%) | 15 | 0 | 24 | — | 24 | () | Kim 2007 [16] | + | 10 | | 10 (100%) | 0 | 0 | 10 | 104.1 | 16 | () | Newcomer 2008 [18] | + | 88 | | 68 (77.3%) | 20 | 0 | 88 | 92 | 16 | () | Schorr 2008 [17] | | 16 | | 12 (75%) | 4 | 1 | 15 | 95 | 56 | () | Pae 2009 [19] | + | 87 | | 87 (100%) | 0 | 13 | 74 | — | 12 | () | Kim 2009 [20] | + | 61 | | 61 (100%) | 0 | 6 | 55 | 67 | 26 | () | Takeuchi 2010 [21] | | 32 | | 32 (100%) | 0 | 6 | 26 | 63.1 | 52 | () |
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BAT = Baseline antipsychotic treatments (prior to switching to aripiprazole; T = typical antipsychotics; SGA = second generation antipsychotics).
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