Research Article

Switching to Aripiprazole as a Strategy for Weight Reduction: A Meta-Analysis in Patients Suffering from Schizophrenia

Table 1

Description of analyzed studies.

Reference in text =in textIndustry-
supported study
Sample size  AgeDiagnosisBATBaseline weight (kilograms)Aripiprazole treatment durationWeight change (P value)
SchizophreniaSchizoaffectiveTSGA

Pigott 2003 [11]+15542.2155 (100%)0116397526 ( )
Casey 2003 [12]+311 210 (65.3%)1012428790.28 ( )
Spurling 2007 [15] 24 9 (37.5%)1502424 ( )
Kim 2007 [16]+10 10 (100%)0010104.116 ( )
Newcomer 2008 [18]+88 68 (77.3%)200889216 ( )
Schorr 2008 [17] 16 12 (75%)41159556 ( )
Pae 2009 [19]+87 87 (100%)0137412 ( )
Kim 2009 [20]+61 61 (100%)06556726 ( )
Takeuchi 2010 [21] 32 32 (100%)062663.152 ( )

BAT = Baseline antipsychotic treatments (prior to switching to aripiprazole; T = typical antipsychotics; SGA = second generation antipsychotics).